Positions

Publications

Academic Article

Year Title
2018 Chemical cross-linking in the structural analysis of protein assemblies.Methods Neuroprotocols.  144:53-63. 2018
2017 An unfolded protein-induced conformational switch activates mammalian IRE1.eLife.  6. 2017
2017 Genomic, transcriptomic, and proteomic approaches towards understanding the molecular mechanisms of salt tolerance in Frankia strains isolated from Casuarina trees.BMC Genomics.  18:633. 2017
2017 An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5.Stem Cell Reports.  8:1488-1496. 2017
2016 The epichaperome is an integrated chaperome network that facilitates tumour survival.Nature Nature: New biology.  538:397-401. 2016
2016 Contributions of Phenoxazone-Based Pigments to the Structure and Function of Nanostructured Granules in Squid Chromatophores.Langmuir.  32:3754-3759. 2016
2015 Molecular responses of Frankia sp. strain QA3 to naphthalene.Canadian Journal of Microbiology.  61:281-292. 2015
2014 Molecular architecture of photoreceptor phosphodiesterase elucidated by chemical cross-linking and integrative modeling.Journal of Molecular Biology.  426:3713-3728. 2014
2014 Copper tolerance in Frankia sp. strain EuI1c involves surface binding and copper transport.Applied Microbiology and Biotechnology.  98:8005-8015. 2014
2014 Elucidating the mechanism of substrate recognition by the bacterial Hsp90 molecular chaperone.Journal of Molecular Biology.  426:2393-2404. 2014
2013 Hdac6 regulates Tip60-p400 function in stem cells.eLife.  2:e01557. 2013
2013 Probing the Structure of Photoreceptor Phosphodiesterase (PDE6) and Its Interactions with Transducin by Cross-linking and Molecular ModelingFASEB Journal.  27. 2013
2013 Proteomic Identification of Preferential Interactions between PDE6 and its Inhibitory SubunitFASEB Journal.  27. 2013
2013 Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5.Cell.  152:276-289. 2013
2012 An orphan kinesin in trypanosomes cooperates with a kinetoplastid-specific kinesin to maintain cell morphology by regulating subpellicular microtubules.Journal of Cell Science.  125:4126-4136. 2012
2012 Transcription factor binding to a DNA zip code controls interchromosomal clustering at the nuclear periphery.Developmental Cell.  22:1234-1246. 2012
2011 Quantitative mass spectrometry reveals the epigenome as a target of arsenic.Chemico-Biological Interactions.  192:113-117. 2011
2011 Identification of cyclophilin-40-interacting proteins reveals potential cellular function of cyclophilin-40.Analytical Biochemistry.  410:257-265. 2011
2010 Finding chimeras: a bioinformatics strategy for identification of cross-linked peptides.Molecular and Cellular Proteomics.  9:25-31. 2010
2010 The real Jurassic Park: the isolation of proteins from microorganisms preserved in amber inclusions for 40 million yearsExpert Review of Proteomics.  7:22. 2010
2009 Acetylated H4K16 by MYST1 protects UROtsa cells from arsenic toxicity and is decreased following chronic arsenic exposure.Toxicology and Applied Pharmacology.  241:294-302. 2009
2009 The zinc finger protein Zn72D and DEAD box helicase Belle interact and control maleless mRNA and protein levels.BMC Molecular Biology.  10:33. 2009
2008 Identification of a novel chromosomal passenger complex and its unique localization during cytokinesis in Trypanosoma brucei.PLoS ONE.  3:e2354. 2008
2008 Histone acetylation and chromatin remodeling are required for UV-B-dependent transcriptional activation of regulated genes in maize.Plant Cell.  20:827-842. 2008
2008 Human Proteinpedia enables sharing of human protein data.Nature Biotechnology.  26:164-167. 2008
2007 Pkh-kinases control eisosome assembly and organization.EMBO Journal.  26:4946-4955. 2007
2007 Hip is a pro-survival substrate of granzyme B.Journal of Biological Chemistry.  282:27865-27874. 2007
2007 The site-specific installation of methyl-lysine analogs into recombinant histones.Cell.  128:1003-1012. 2007
2006 Isotope-coded and affinity-tagged cross-linking (ICATXL): an efficient strategy to probe protein interaction surfaces.Journal of the American Chemical Society.  128:10362-10363. 2006
2006 Identification of novel quaternary domain interactions in the Hsp90 chaperone, GRP94.Protein Science.  15:1260-1269. 2006
2006 Mapping post-translational modifications of the histone variant MacroH2A1 using tandem mass spectrometry.Molecular and Cellular Proteomics.  5:194-203. 2006
2004 Unraveling the interface of signal recognition particle and its receptor by using chemical cross-linking and tandem mass spectrometry.Proceedings of the National Academy of Sciences of the United States of America.  101:16454-16459. 2004
2002 Efficient Cs2CO3-promoted solution and solid phase synthesis of carbonates and carbamates in the presence of TBAITetrahedron.  58:3329-3347. 2002
1999 Alkyl Carbonates: Efficient Three Component Coupling of Aliphatic Alcohols, CO(2), and Alkyl Halides in the Presence of Cs(2)CO(3).Journal of Organic Chemistry.  64:4578-4579. 1999
1999 Identification of tyrosine sulfation in Conus pennaceus conotoxins alpha-PnIA and alpha-PnIB: further investigation of labile sulfo- and phosphopeptides by electrospray, matrix-assisted laser desorption/ionization (MALDI) and atmospheric pressure MALDI mass spectrometry.Journal of Mass Spectrometry.  34:447-454. 1999
1999 Cesium promoted O-alkylation of alcohols for the efficient ether synthesisTetrahedron Letters.  40:1843-1846. 1999
1999 Cs2CO3 promoted O-alkylation of alcohols for the preparation of mixed alkyl carbonatesTetrahedron Letters.  40:1847-1850. 1999
Ly-Sha Ee, Kurtis N. McCannell, Yang Tang, 2 Nancy Fernandes, 2 W. Rod Hardy, Michael R. Green
Sample Preparation in Biological Mass Spectrometry

Chapter

Year Title
2011 Revisiting Jurassic Park: The Isolation of Proteins from Amber Encapsulated Organisms Millions of Years Old.  925-938. 2011

Teaching Activities

  • Persp Biochem/Mole&Cell Bio Taught course 2018
  • Protein Structure & Function Taught course 2018
  • Rsrch Exp/MCBS Taught course 2018
  • Doctoral Research Taught course 2018
  • Doctoral Research Taught course 2018
  • Doctoral Research Taught course 2018
  • Principles of Biochemistry II Taught course 2018
  • Principles of Biochemistry II Taught course 2018
  • Rsrch Exp/MCBS Taught course 2017 - 2018
  • Doctoral Research Taught course 2017
  • Persp Biochem/Mole&Cell Bio Taught course 2017
  • Protein Structure & Function Taught course 2017
  • Rsrch Exp/MCBS Taught course 2017
  • Doctoral Research Taught course 2017
  • Doctoral Research Taught course 2017
  • Principles of Biochemistry II Taught course 2017
  • Principles of Biochemistry II Taught course 2017
  • Rsrch Exp/MCBS Taught course 2017
  • Doctoral Research Taught course 2016
  • Opport/Biochem/Molec/Cell Biol Taught course 2016
  • Doctoral Research Taught course 2016
  • Principles of Biochemistry II Taught course 2016
  • Principles of Biochemistry II Taught course 2016
  • Rsrch Exp/MCBS Taught course 2016
  • Adv Rsrch Exp/MCBS Taught course 2015
  • Doctoral Research Taught course 2015
  • Doctoral Research Taught course 2015
  • General Biochemistry Taught course 2015
  • General Biochemistry Taught course 2015
  • Opport/Biochem/Molec/Cell Biol Taught course 2014
  • Proteomics for Biol Discovery Taught course 2014
  • Doctoral Research Taught course 2014
  • General Biochemistry Taught course 2014
  • General Biochemistry Taught course 2014
  • Education And Training

    Full Name

  • Feixia Chu