The advancement in wireless body sensor network and micro fabrication techniques have created a great opportunity for using miniaturized wireless microelectronic devices in a variety of health and life science applications. With big data and machine learning exponential growth in healthcare and clinical treatments, accurate analysis of clinical data helps in early disease detection, patient care, and community services. Keeping this mind, our research interests lie in 1) designing and implementing novel sensors and remote health monitoring systems, (2) IoT based wearable biosensor for personalized mobile health, (3) reliable and secure data communication, and (4) early disease detection using machine learning.