Research Areas research areas

Selected Publications

Academic Article

Year Title
2024 Dopaminergic lesions of the anterior cingulate cortex of rats increase vulnerability to salient distractors.European Journal of Neuroscience.  59:3353-3375. 2024
2022 The enduring effect of prenatal protein malnutrition on brain anatomy, physiology and behavior.Nutritional Neuroscience.  25:1392-1399. 2022
2021 In vivo microdialysis shows differential effects of prenatal protein malnutrition and stress on norepinephrine, dopamine, and serotonin levels in rat orbital frontal cortex.Behavioral Neuroscience.  135:629-641. 2021
2019 Prenatal Protein Malnutrition Leads to Hemispheric Differences in the Extracellular Concentrations of Norepinephrine, Dopamine and Serotonin in the Medial Prefrontal Cortex of Adult Rats.Frontiers in Neuroscience.  13:136. 2019
2019 Prenatal Protein Malnutrition Produces Resistance to Distraction Similar to Noradrenergic Deafferentation of the Prelimbic Cortex in a Sustained Attention Task.Frontiers in Neuroscience.  13:123. 2019
2017 Evidence for a role of corticopetal, noradrenergic systems in the development of executive function.Neurobiology of Learning and Memory.  143:94-100. 2017
2017 Exposure to sevoflurane anesthesia during development does not impair aspects of attention during adulthood in rats.Neurotoxicology and Teratology.  60:87-94. 2017
2016 DNA Methylation Signatures of Early Childhood Malnutrition Associated With Impairments in Attention and Cognition.Biological Psychiatry.  80:765-774. 2016
2016 Age-related changes in prefrontal norepinephrine transporter density: The basis for improved cognitive flexibility after low doses of atomoxetine in adolescent rats.Brain Research.  1641:245-257. 2016
2016 Prenatal protein level impacts homing behavior in Long-Evans rat pups.Nutritional Neuroscience.  19:187-195. 2016
2015 Prenatal protein malnutrition decreases KCNJ3 and 2DG activity in rat prefrontal cortex.Neuroscience.  286:79-86. 2015
2015 Cognitive control and the anterior cingulate cortex: how conflicting stimuli affect attentional control in the rat.Journal of Physiology: Paris.  109:95-103. 2015
2014 Neuropsychological outcomes at midlife following moderate to severe malnutrition in infancy.Neuropsychology.  28:530-540. 2014
2014 Interaction of age, cognitive function, and gait performance in 50-80-year-olds.Age.  36:9693. 2014
2014 Prenatal malnutrition leads to deficits in attentional set shifting and decreases metabolic activity in prefrontal subregions that control executive function.Developmental Neuroscience.  36:532-541. 2014
2012 Differential sensitivity to psychostimulants across prefrontal cognitive tasks: differential involvement of noradrenergic α₁ - and α₂-receptors.Biological Psychiatry.  71:467-473. 2012
2011 Atomoxetine facilitates attentional set shifting in adolescent rats.Developmental Cognitive Neuroscience.  1:552-559. 2011
2011 Attentional effects of lesions to the anterior cingulate cortex: how prior reinforcement influences distractibility.Behavioral Neuroscience.  125:360-371. 2011
2011 Adolescent rats show cognitive rigidity in a test of attentional set shifting.Developmental Psychobiology.  53:391-401. 2011
2008 Atomoxetine reverses attentional deficits produced by noradrenergic deafferentation of medial prefrontal cortex.Psychopharmacology.  200:39-50. 2008
2008 Noradrenergic, but not cholinergic, deafferentation of prefrontal cortex impairs attentional set-shifting.Neuroscience.  153:63-71. 2008
2008 Cholinergic deafferentation of prefrontal cortex increases sensitivity to cross-modal distractors during a sustained attention task.The Journal of Neuroscience.  28:2642-2650. 2008
2007 Experimental sleep fragmentation impairs attentional set-shifting in rats.Sleep.  30:52-60. 2007
2005 Cholinergic deafferentation of the entorhinal cortex in rats impairs encoding of novel but not familiar stimuli in a delayed nonmatch-to-sample task.The Journal of Neuroscience.  25:10273-10281. 2005
2005 Acetylcholine in the orbitofrontal cortex is necessary for the acquisition of a socially transmitted food preference.Learning and Memory.  12:302-306. 2005
2004 High acetylcholine levels set circuit dynamics for attention and encoding and low acetylcholine levels set dynamics for consolidation.Progress in Brain Research.  145:207-231. 2004
2002 Selective behavioral and neurochemical effects of cholinergic lesions produced by intrabasalis infusions of 192 IgG-saporin on attentional performance in a five-choice serial reaction time task.The Journal of Neuroscience.  22:1905-1913. 2002
2002 It's time to pay attention to attention in aging.Learning and Memory.  9:151-152. 2002
2001 Distinct changes in cortical acetylcholine and noradrenaline efflux during contingent and noncontingent performance of a visual attentional task.The Journal of Neuroscience.  21:4908-4914. 2001
2000 The role of cortical cholinergic afferent projections in cognition: impact of new selective immunotoxins.Behavioural Brain Research.  115:251-263. 2000
2000 Development of a method for intraparenchymal infusions of 192 IgG-saporin: a comment on Pizzo et al. (1999).Journal of Neuroscience Methods.  96:169-170. 2000
1999 Effects of ovariectomy, 192 IgG-saporin-induced cortical cholinergic deafferentation, and administration of estradiol on sustained attention performance in ratsBehavioral Neuroscience.  113:1216-1232. 1999
1999 Effects of ovariectomy, 192 IgG-saporin-induced cortical cholinergic deafferentation, and administration of estradiol on sustained attention performance in rats.Behavioral Neuroscience.  113:1216-1232. 1999
1999 Enhancement of sustained attention performance by the nicotinic acetylcholine receptor agonist ABT-418 in intact but not basal forebrain-lesioned rats.Psychopharmacology.  144:175-182. 1999
1998 Sustained attention performance in rats with intracortical infusions of 192 IgG-saporin-induced cortical cholinergic deafferentation: effects of physostigmine and FG 7142.Behavioral Neuroscience.  112:1519-1525. 1998
1998 Assessment of sustained and divided attention in rats: aspects of validity; [comment].Psychopharmacology.  138:260-262. 1998
1997 Lack of effects of lesions of the dorsal noradrenergic bundle on behavioral vigilance.Behavioral Neuroscience.  111:646-652. 1997
1996 Neuronal mechanisms mediating drug-induced cognition enhancement: cognitive activity as a necessary intervening variable.Cognitive Brain Research.  3:329-343. 1996
1996 Behavioral vigilance following infusions of 192 IgG-saporin into the basal forebrain: selectivity of the behavioral impairment and relation to cortical AChE-positive fiber density.Behavioral Neuroscience.  110:247-265. 1996
1995 Effects of chlordiazepoxide and scopolamine, but not aging, on the detection and identification of conditional visual stimuli.Journal of Gerontology Series A: Biological Sciences and Medical Sciences.  50:B90-B96. 1995
1995 Behavioral vigilance in rats: task validation and effects of age, amphetamine, and benzodiazepine receptor ligands.Psychopharmacology.  117:340-357. 1995
1994 Crossmodal divided attention in rats: effects of chlordiazepoxide and scopolamine.Psychopharmacology.  115:213-220. 1994
The lasting effect of the maternal environment on brain anatomy, physiology and behavior – how adult behavior is shaped by prenatal influences.


Year Title
2014 Nervous System Research with RIP Conjugates: From Determination of Function to Therapy.  253-269. 2014

Conference Paper

Year Title
2015 Prenatal Protein Malnutrition Increases Activation of Parvalbumin Interneurons but Decreases Overall Activation in the Prefrontal Cortex of Adult RatsThe FASEB Journal. 2015
2009 Effects of a diet rich in omega-3 essential fatty acids on behavior in an attentional task and monoamine transmitter levels in the medial prefrontal cortex of adolescent ratsThe FASEB Journal. 2009
2008 A comparison of serotonin, dopamine, and norepinephrine in the medial prefrontal cortex of male and female adolescent and adult ratsFundamental and Clinical Pharmacology. 129-129. 2008
2000 Behavioural and neurochemical assessment of the effects of cholinergic deafferentation produced by 192 IgG-saporin on visual attention in a 5-choice serial reaction time task.European Journal of Neuroscience. 201-201. 2000
1999 Behavioural and neurochemical evidence for a role of cortical acetylcholine in visual attentionBritish Journal of Pharmacology. U114-U114. 1999
1996 New approaches to determine the neuronal mechanisms of age-related impairments in attentional functionsInternational Journal of Psychology. 2083-2083. 1996

Teaching Activities

  • Attention Disorders Taught course
  • Honors/Human Brain Taught course
  • Advanced Research Experience Taught course 2023
  • Drugs and Behavior Taught course 2023
  • Drugs and Behavior Taught course 2023
  • Attention Disorders Taught course 2022
  • Doctoral Research Taught course 2022
  • Psychobiology Taught course 2022
  • Attention Disorders Taught course 2022
  • Drugs and Behavior Taught course 2022
  • Adv Sem/Physiological Psych Taught course 2021
  • Pract&Sem/Teaching Psychology Taught course 2021
  • Drugs and Behavior Taught course 2021
  • Psychobiology Taught course 2021
  • Honors/Human Brain Taught course 2020
  • Pract&Sem/Teaching Psychology Taught course 2020
  • Drugs and Behavior Taught course 2020
  • Attention Disorders Taught course 2019
  • Pract&Sem/Teaching Psychology Taught course 2019
  • Drugs and Behavior Taught course 2019
  • Psychobiology Taught course 2019
  • Honors/Human Brain Taught course 2018
  • Topics Neuroscience & Behavior Taught course 2018
  • Attention Disorders Taught course 2018
  • Drugs and Behavior Taught course 2018
  • Attention Disorders Taught course 2017
  • Honors/Human Brain Taught course 2017
  • Rsrch Exp/Psychology Taught course 2017
  • Drugs and Behavior Taught course 2016
  • Topics Neuroscience & Behavior Taught course 2016
  • Adv Sem/Physiological Psych Taught course 2016
  • Attention Disorders Taught course 2016
  • Honors Senior Thesis Taught course 2016
  • Drugs and Behavior Taught course 2015
  • Honors Senior Thesis Taught course 2015
  • Psychobiology Taught course 2015
  • Attention Disorders Taught course 2015
  • Psychobiology Taught course 2015
  • Senior Honors Thesis Taught course 2015
  • Adv Rsrch Exp/Psychology Taught course 2014
  • Drugs and Behavior Taught course 2014
  • Drugs and Behavior Taught course 2014
  • Senior Honors Thesis Taught course 2014
  • Attention Disorders Taught course 2014
  • Graduate Pro-seminar Taught course 2014
  • Rsrch Exp/Psychology Taught course 2014
  • Education And Training

  • B.A. Psychology, Bradley University
  • M.A. Psychology, Ohio State University
  • Ph.D. Psychology, Ohio State University
  • Full Name

  • Jill McGaughy