Heavy metal resistance patterns of Frankia strains.

Academic Article


  • The sensitivity of 12 Frankia strains to heavy metals was determined by a growth inhibition assay. In general, all of the strains were sensitive to low concentrations (<0.5 mM) of Ag(1+), AsO(2)(1-), Cd(2+), SbO(2)(1-), and Ni(2+), but most of the strains were less sensitive to Pb(2+) (6 to 8 mM), CrO(4)(2-) (1.0 to 1.75 mM), AsO(4)(3-) (>50 mM), and SeO(2)(2-) (1.5 to 3.5 mM). While most strains were sensitive to 0.1 mM Cu(2+), four strains were resistant to elevated levels of Cu(2+) (2 to 5 mM and concentrations as high as 20 mM). The mechanism of SeO(2)(2-) resistance seems to involve reduction of the selenite oxyanion to insoluble elemental selenium, whereas Pb(2+) resistance and Cu(2+) resistance may involve sequestration or binding mechanisms. Indications of the resistance mechanisms for the other heavy metals were not as clear.
  • Authors

  • Richards, Joel W
  • Krumholz, Glenn D
  • Chval, Matthew S
  • Tisa, Louis
  • Status

    Publication Date

  • February 2002
  • Keywords

  • Actinomycetales
  • Culture Media
  • Drug Resistance, Bacterial
  • Metals, Heavy
  • Microbial Sensitivity Tests
  • Digital Object Identifier (doi)

    Start Page

  • 923
  • End Page

  • 927
  • Volume

  • 68
  • Issue

  • 2