Collaborative Research: Small Molecules as Chemical Probes of Protein Dynamics and Protein-Protein Interactions

Grant

Date/time Interval

August 15, 2015 - July 31, 2019

Awarded By

National Science Foundation (NSF)

Total Award Amount

USD 218439

Sponsor Award Id

961152880

Local Award Id

15-328

Contributor

Vashisth, Harish Principal Investigator

Supported Publications Or Other Works

An Interhelical Salt Bridge Controls Flexibility and Inhibitor Potency for Regulators of G-protein Signaling Proteins 4, 8, and 19. Academic Article

Capturing Differences in Dynamics of Structurally Similar Signaling Proteins Conference Paper

Interplay of cysteine exposure and global protein dynamics in small-molecule recognition by a regulator of G-protein signaling protein. Academic Article

Interpreting hydrogen-deuterium exchange rates in proteins using atomistic simulations Academic Article

Predicting hydrogen-deuterium exchange rates in proteins using molecular dynamics simulations Conference Paper

Role of protein dynamics in allosteric targeting of protein-protein interfaces Conference Paper