Positions

Research Areas research areas

Overview

  • Dr. Duoduo (Dora) Wang is an Assistant Professor of Plant Physiology at the University of New Hampshire and an Associate Editor for The Journal of Horticultural Science & Biotechnology. She earned her Ph.D. in Plant Biotechnology from the University of Nottingham in 2018, followed by postdoctoral research at the University of Florida and Cornell University.

    Dr. Wang’s research focuses on uncovering the genetic and molecular mechanisms of fruit softening, using tomato as a model system. As a key horticultural crop, tomato plays a vital role in both fresh and processed markets, yet its short shelf life leads to significant postharvest losses. Softening, a ripening-associated process, directly affects fruit quality, shelf life, and disease resistance. Due to its well-characterized genetics, short life cycle, and efficient transformation system, tomato serves as an ideal model for studying softening in climacteric fruits, with insights applicable to other fleshy fruits.

    Striking a balance between controlling softening and preserving key quality traits such as flavor is essential for improving fruit quality and ensuring sustainability in the food supply chain. Dr. Wang’s lab integrates molecular genetics, bioinformatics, and genomics to tackle key unresolved questions in this field. The lab welcomes highly motivated graduate and undergraduate students seeking hands-on experience in plant physiology, genetics, and molecular biology.
  • Selected Publications

    Academic Article

    Year Title
    2025 Engineering tomato disease resistance by manipulating susceptibility genes.Front Genome Ed.  7:1537148. 2025
    2024 Double CRISPR knockout of pectin degrading enzymes improves tomato shelf‐life while ensuring fruit qualityPlants People Planet.  6:330-340. 2024
    2023 Elucidating the role of SlXTH5 in tomato fruit softeningHorticultural Plant Journal.  9:777-788. 2023
    2023 Pectin: a critical component in cell-wall-mediated immunity.Trends in Plant Science.  28:10-13. 2023
    2022 Molecular and biochemical basis of softening in tomato.Mol Hortic.  2:5. 2022
    2021 Development and application of molecular markers for TSW (thousand-seed weight) related gene BnaGRF7.C02 in Brassica napusOil Crop Science.  6:145-150. 2021
    2021 Host susceptibility factors render ripe tomato fruit vulnerable to fungal disease despite active immune responses.Journal of Experimental Botany.  72:2696-2709. 2021
    2019 Generation of a selectable marker free, highly expressed single copy locus as landing pad for transgene stacking in sugarcanePlant Molecular Biology.  100:247-263. 2019
    2018 Fruit Softening: Revisiting the Role of PectinTrends in Plant Science.  23:302-310. 2018
    2017 Tomato Flavor: Lost and Found?Molecular Plant.  10:782-784. 2017
    2016 Genetic improvement of tomato by targeted control of fruit softeningNature Biotechnology.  34:950-952. 2016
    2013 Antifungal Activity of Hypothemycin against Peronophythora Litchii In Vitro And In VivoJournal of Agricultural and Food Chemistry.  61:10091-10095. 2013
    Advances and Challenges in CRISPR/Cas-Based Fungal Genome Engineering for Secondary Metabolite Production: A ReviewJournal of Fungi.  9:362-362.
    Characterisation of CRISPR mutants targeting genes modulating pectin degradation in ripening tomatoPlant Physiology.  pp.01187.2018-pp.01187.2018.
    Genome-wide identification of the pectin methylesterase inhibitor genes in Brassica napus and expression analysis of selected membersFrontiers in Plant Science.  13.
    Modification of Pectin and Hemicellulose Polysaccharides in Relation to Aril Breakdown of Harvested Longan FruitInternational Journal of Molecular Sciences.  14:23356-23368.
    Multiallelic, Targeted Mutagenesis of Magnesium Chelatase With CRISPR/Cas9 Provides a Rapidly Scorable Phenotype in Highly Polyploid SugarcaneFrontiers in Genome Editing.  3.
    Pectin, Lignin and Disease Resistance in Brassica napus L.: An UpdateHorticulturae.  9:112-112.
    The Discovery of the Potential Attractive Compounds of Bactrocera dorsalis (Hendel)Horticulturae.  10:299-299.
    The Effects of Nine Compounds on Aldehyde-Oxidase-Related Genes in Bactrocera dorsalis (Hendel)Genes.  15:35-35.

    Article

    Year Title
    2020 Tomato fruit susceptibility to fungal disease can be uncoupled from ripening by suppressing susceptibility factors 2020

    Education And Training

  • Ph.D. Plant Sciences, University of Nottingham
  • Full Name

  • Duoduo Wang