Positions

Research Areas research areas

Overview

  • I received a DVM from the Cummings School of Veterinary Medicine at Tufts University in 2011, after which I completed a 3 years residency in Veterinary Anatomic Pathology at the Diagnostic Center for Population and Animal Health at Michigan State University, and one year of post-doctoral work in microbial pathogenesis.

    I joined the New Hampshire Veterinary Diagnostic Laboratory (NHVDL) and UNH in 2015. My clinical work consists of diagnostic and investigational pathology serving primary care veterinarians, livestock producers, zoological collections, researchers, wildlife agencies, and rehabilitators. My research is currently comprised of two main foci in the broader context of One Health: (1) emerging and zoonotic wildlife disease discovery, and (2) comparative microbial genomics. Both areas of research have their basis in observations from diagnostic and research submissions to the NHVDL sections of pathology and microbiology. Active research in both areas relies on collaboration with multiple researchers and diagnosticians regionally and nationally.
  • Selected Publications

    Academic Article

    Year Title
    2020 Concurrent Infection of Skunk Adenovirus-1, Listeria monocytogenes, and a Regionally Specific Clade of Canine Distemper Virus in One Gray Fox (Urocyon cinereoargenteus) and Concurrent Listeriosis and Canine Distemper in a Second Gray Fox.Pathogens.  9:591-591. 2020
    2020 Pathology in Practice.Journal of the American Veterinary Medical Association.  257:49-52. 2020
    2020 Population genomics of Staphylococcus pseudintermedius in companion animals in the United States.Commun Biol.  3:282. 2020
    2020 Avian coxiellosis in nine psittacine birds, one black-browed barbet, and one paradise tanager.Avian Pathology.  49:268-274. 2020
    2019 Necrotizing Ventriculitis in Fledgling Chimney Swifts (Chaetura Pelagica) Associated With a Novel Adenovirus, Chimney Swift Adenovirus-1 (CsAdV-1).Veterinary Pathology.  56:907-914. 2019
    2019 Atypical Dermatophytosis in 12 North American Porcupines (Erethizon dorsatum) from the Northeastern United States 2010-2017.Pathogens.  8:171-171. 2019
    2019 Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia.Blood Adv.  3:2598-2603. 2019
    2019 Infection of eight mesocarnivores in New Hampshire and Vermont with a distinct clade of canine distemper virus in 2016-2017.Journal of Veterinary Diagnostic Investigation.  31:562-567. 2019
    2019 Identification of a Novel Gammaherpesvirus in Canada lynx (Lynx canadensis).Viruses.  11:363-363. 2019
    2019 Fatal bronchopneumonia caused by skunk adenovirus 1 in an African pygmy hedgehog.Journal of Veterinary Diagnostic Investigation.  31:103-106. 2019
    2018 Biphasic malignant melanoma adenocarcinoma in the digit of a dog.Journal of Veterinary Diagnostic Investigation.  30:315-318. 2018
    2017 Pathology in Practice. Systemic bibersteiniosis .Journal of the American Veterinary Medical Association.  251:405-407. 2017
    2017 A bioluminescent Pseudomonas aeruginosa wound model reveals increased mortality of type 1 diabetic mice to biofilm infection.Journal of wound care.  26:S24-S33. 2017
    2016 TREATMENT OF RENAL CARCINOMA IN A BINTURONG (ARCTICTIS BINTURONG) WITH NEPHRECTOMY AND A TYROSINE KINASE INHIBITOR.Journal of Zoo and Wildlife Medicine.  47:1109-1113. 2016
    2016 Polysorbates prevent biofilm formation and pathogenesis of Escherichia coli O104:H4.Biofouling.  32:1131-1140. 2016
    2015 Pathology in Practice. Lymphomatoid granulomatosis of lung tissue and mediastinal lymph node in a dog.Journal of the American Veterinary Medical Association.  247:1113-1116. 2015
    2015 Sarcocystis spp. Infection in two Red Panda Cubs (Ailurus fulgens).Journal of Comparative Pathology.  153:185-189. 2015
    2015 The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits the Mycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence.Antimicrobial Agents and Chemotherapy.  59:4436-4445. 2015
    2014 What is your diagnosis?Journal of Avian Medicine and Surgery.  28:343-347. 2014
    2014 Necrotizing and eosinophilic masticatory myositis in farmed mink: a preliminary description.Journal of Comparative Pathology.  151:217-227. 2014
    2014 Pathology in practice. Parvoviral myocarditis.Journal of the American Veterinary Medical Association.  244:1155-1157. 2014
    2014 Necrotizing and Eosinophilic Masticatory Myositis in Farmed Mink: a Preliminary DescriptionJournal of Comparative Pathology.  151:217-227. 2014
    2013 Glaucoma associated with uveal cysts and goniodysgenesis in American Bulldogs: a case series.Veterinary Ophthalmology.  16:377-385. 2013
    2013 CHONDROBLASTIC OSTEOSARCOMA IN TWO RELATED SPINY-TAILED MONITOR LIZARDS (VARANUS ACANTHURUS)Seminars in Avian and Exotic Pet Medicine Journal of Exotic Pet Medicine.  22:265-269. 2013
    2013 Pathology in practice. Arteriothromboembolism.Journal of the American Veterinary Medical Association.  242:931-933. 2013

    Conference Paper

    Year Title
    Dermatophytosis in North American porcupines (Erethizon dorsatum)

    Teaching Activities

  • Experience in Vet DIagnostics Taught course 2021
  • Senior Honors Thesis Taught course 2021
  • Experience in Vet DIagnostics Taught course 2020
  • Pathologic Basis of Disease Taught course 2020
  • Senior Honors Thesis Taught course 2020
  • Grand Rounds Taught course 2020
  • Senior Honors Thesis Taught course 2020
  • Grand Rounds Taught course 2019
  • Pathologic Basis of Disease Taught course 2019
  • Adv Rsrch Exp/MCBS Taught course 2019
  • Field Experience Taught course 2019
  • Grand Rounds Taught course 2019
  • Investigations Biomedical Sci Taught course 2019
  • Pathologic Basis of Disease Taught course 2019
  • Senior Honors Thesis Taught course 2019
  • Adv Rsrch Exp/MCBS Taught course 2018 - 2019
  • Field Experience Taught course 2018
  • Grand Rounds Taught course 2018
  • Histology Taught course 2018
  • Investigations Biomedical Sci Taught course 2018
  • Senior Honors Thesis Taught course 2018
  • Grand Rounds Taught course 2018
  • Investigations Biomedical Sci Taught course 2018
  • Pathologic Basis of Disease Taught course 2018
  • Grand Rounds Taught course 2017
  • Investigations Biomedical Sci Taught course 2017
  • Field Experience Taught course 2017
  • Investigations Taught course 2017
  • Pathologic Basis of Disease Taught course 2017
  • Field Experience Taught course 2016
  • Field Experience Taught course 2016
  • Pathologic Basis of Disease Taught course 2016
  • Education And Training

    Full Name

  • David Needle