Survival and repair of potentially lethal radiation damage in confluent vascular smooth muscle cell cultures.

Academic Article

Abstract

  • Confluent cultures of rat aortic smooth muscle cells demonstrated dose-dependent potentially lethal damage repair (PLDR), with an average repair factor of 4 for a 10 Gy dose. PLDR occurred with a half-time of 2 hours and was nearly maximal by 8 h. Among other factors, PLDR may contribute to the radioresistance of large blood vessels.
  • Authors

  • Rosen, EM
  • Goldberg, ID
  • Myrick, KV
  • Halpin, Patricia
  • Levenson, SE
  • Status

    Publication Date

  • February 1986
  • Published In

    Keywords

  • Animals
  • Aorta
  • Cell Line
  • Cell Survival
  • Cells, Cultured
  • Dose-Response Relationship, Radiation
  • Male
  • Muscle, Smooth, Vascular
  • Radiation Dosage
  • Radiation Injuries, Experimental
  • Rats
  • Rats, Inbred Strains
  • Digital Object Identifier (doi)

    Pubmed Id

  • 3704190
  • Start Page

  • 159
  • End Page

  • 163
  • Volume

  • 5
  • Issue

  • 2