Effects of thalamic and olfactory cortical lesions on continuous olfactory delayed nonmatching-to-sample and olfactory discrimination in rats (Rattus norvegicus).

Academic Article

Abstract

  • We conducted 2 studies to determine the importance of several brain systems for remembering odorants in a go/no-go delayed nonmatching-to-sample (DNMTS) task. In Experiment 1, impairments were observed for lesions of pyriform cortex or (to a lesser extent) the lateral internal medullary lamina of thalamus. Lesions of the entorhinal cortex or the mediodorsal (MDn) or the paracentral and centrolateral (PC-CL) thalamic nuclei did not affect DNMTS. In Experiment 2, an impairment comparable to the pyriform lesion was observed for a lesion of the intralaminar nuclei (PC-CL plus the central medial nucleus) but not for a larger lesion of MDn. None of the lesions in either study affected the ability to learn a 2-choice odor discrimination using go/no-go procedures comparable with the DNMTS task.
  • Authors

  • Zhang, Y
  • Burk, JA
  • Glode, BM
  • Mair, Robert
  • Status

    Publication Date

  • February 1998
  • Published In

    Keywords

  • Animals
  • Attention
  • Brain Mapping
  • Discrimination Learning
  • Male
  • Mental Recall
  • Olfactory Pathways
  • Rats
  • Retention (Psychology)
  • Smell
  • Thalamic Nuclei
  • Digital Object Identifier (doi)

    Pubmed Id

  • 9517814
  • Start Page

  • 39
  • End Page

  • 53
  • Volume

  • 112
  • Issue

  • 1