Is how science is conducted legitimate? Are scientists trustworthy? Whether the public answers “yes” to these questions is critical for science communicators. We explore how social factors affect public perceptions of the practice of science, and then test how those beliefs relate to views about how scientists engage with the public and policy making. Our results show that political ideology and religiosity affect these views. However, more importantly, respondents' concerns about the integrity of the scientific process are the strongest predictor of views about scientists' behavior, providing a focus area for future communication efforts in support of science-based decision making.