Resilin, an insect structural protein, exhibits rubber-like elasticity characterized by low stiffness, high extensibility, efficient energy storage, and exceptional resilience and fatigue lifetime. The outstanding mechanical properties of natural resilin have motivated recent research in the engineering of resilin-like polypeptide-based biomaterials, with a wide range of applications including use as bio-rubbers, nanosprings, elements in biosensors, and tissue engineering scaffolds.