Abstract. Agricultural production and food prices are affected by hydroclimatic extremes. There has been a large literature measuring the impacts of individual extreme events (heat stress or water stress) on agricultural and human systems. Yet, we lack a comprehensive understanding of the significance and the magnitude of the impacts of compound extremes. Here, we combine a high-resolution weather product with fine-scale outputs of a hydrological model to construct functional indicators of compound hydroclimatic extremes for agriculture. Then, we measure the impacts of individual and compound extremes on crop yields focusing on the United States during the 1981–2015 period. Supported by statistical evidence, we confirm that wet heat is more damaging than dry heat for crops. We show that the average damage from heat stress has been up to four times more severe when combined with water stress; and the value of water experiences a four-fold increase on hot days. In a robust framework with only a few parameters of compound extremes, this paper also improves our understanding of the conditional marginal value (or damage) of water in crop production. This value is critically important for irrigation water demand and farmer decision-making – particularly in the context of supplemental irrigation and sub-surface drainage.