Stable and reproducible electronic conduction through DNA molecular junctions

Academic Article


  • This letter presents the observation of stable and reproducible electronic conduction through double stranded (ds) DNA molecules in a nominally dry state. Stable conduction was realized by immobilizing 15 base-pair guanine:cytosine rich dsDNA within gold nanogap junctions, stabilizing the dsDNA with a polycation, and characterizing in nitrogen. In air, the current levels decrease with successive voltage scans likely due to oxidation of the guanine bases under bias. In nitrogen, reproducible current-voltage traces are observed and the current levels at specific bias points are stable with time. The stability allows comprehensive electrical studies and could enable conductance-based DNA sensors.
  • Authors

  • Mahapatro, Ajit K
  • Lee, Gil U
  • Jeong, Kyung Jae
  • Janes, David B
  • Status

    Publication Date

  • August 24, 2009
  • Has Subject Area

    Published In

    Digital Object Identifier (doi)

    Start Page

  • 083106
  • Volume

  • 95
  • Issue

  • 8