Positions

Publications

Academic Article

Year Title
2018 Epigenetics and Sphingolipid Metabolism in Health and Disease.Int J Biopharm Sci.  1:105-105. 2018
2018 Therapeutic effect of Northern Labrador tea extracts for acute myeloid leukemia.Phytotherapy Research.  32:1636-1641. 2018
2018 Combinatorial Efficacy of Quercitin and Nanoliposomal Ceramide for Acute Myeloid LeukemiaInternational Journal of Biopharmaceutical Sciences.  1:106-106. 2018
2018 Therapeutic Effect of Blueberry Extracts for Acute Myeloid Leukemia.Int J Biopharm Sci.  1. 2018
2016 Acid ceramidase is upregulated in AML and represents a novel therapeutic target.Oncotarget.  7:83208-83222. 2016
2016 Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia.Journal of Lipid Research.  57:1231-1242. 2016
2015 Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics.Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids.  1851:919-928. 2015
2014 Extracts of Devil's club (Oplopanax horridus) exert therapeutic efficacy in experimental models of acute myeloid leukemia.Phytotherapy Research.  28:1308-1314. 2014
2014 Maritoclax induces apoptosis in acute myeloid leukemia cells with elevated Mcl-1 expression.Cancer Biology and Therapy.  15:1077-1086. 2014
2014 Cholecystokinin mediates progression and metastasis of pancreatic cancer associated with dietary fat.Digestive Diseases and Sciences.  59:1180-1191. 2014
2013 Ceramide 1-phosphate mediates endothelial cell invasion via the annexin a2-p11 heterotetrameric protein complex.Journal of Biological Chemistry.  288:19726-19738. 2013
2013 PhotoImmunoNanoTherapy reveals an anticancer role for sphingosine kinase 2 and dihydrosphingosine-1-phosphate.ACS Nano.  7:2132-2144. 2013
2013 Gaucher's disease and cancer: a sphingolipid perspective.Critical Reviews in Oncogenesis.  18:221-234. 2013
2012 Ceramide kinase regulates TNFα-stimulated NADPH oxidase activity and eicosanoid biosynthesis in neuroblastoma cells.Cellular Signalling.  24:1126-1133. 2012
2012 Calcium Phosphosilicate Nanoparticles for Imaging and Photodynamic Therapy of CancerDiscovery medicine.  13:275-285. 2012
2012 Neutral sphingomyelinase activation precedes NADPH oxidase-dependent damage in neurons exposed to the proinflammatory cytokine tumor necrosis factor-α.Journal of Neuroscience Research.  90:229-242. 2012
2011 Exogenous ceramide-1-phosphate reduces lipopolysaccharide (LPS)-mediated cytokine expression.Journal of Biological Chemistry.  286:44357-44366. 2011
2011 Ceramide-Based Therapeutics for the Treatment of CancerAnti-Cancer Agents in Medicinal Chemistry Current Medicinal Chemistry - Anti-Cancer Agents.  11:911-919. 2011
2011 Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer.Cancer Biology and Therapy.  12:574-585. 2011
2011 Targeted indocyanine-green-loaded calcium phosphosilicate nanoparticles for in vivo photodynamic therapy of leukemia.ACS Nano.  5:5325-5337. 2011
2011 Nanoliposomal ceramide prevents in vivo growth of hepatocellular carcinoma.Gut.  60:695-701. 2011
2011 Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.Nature Medicine.  17:55-63. 2011
2010 Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance.Cancer Biology and Therapy.  10:1126-1136. 2010
2010 Metabolism of short-chain ceramide by human cancer cells--implications for therapeutic approaches.Biochemical Pharmacology.  80:308-315. 2010
2010 Bioconjugation of calcium phosphosilicate composite nanoparticles for selective targeting of human breast and pancreatic cancers in vivo.ACS Nano.  4:1279-1287. 2010
2009 Proinflammatory cytokines provoke oxidative damage to actin in neuronal cells mediated by Rac1 and NADPH oxidase.Molecular and Cellular Neurosciences.  41:274-285. 2009
2008 Near-infrared emitting fluorophore-doped calcium phosphate nanoparticles for in vivo imaging of human breast cancer.ACS Nano.  2:2075-2084. 2008
2007 Wild alaskan blueberry extracts inhibit a magnesium-dependent neutral sphingomyelinase activity in neurons exposed to TNF alphaCurrent Topics in Nutraceutical Research.  5:183-188. 2007

Patents And Disclosures

Year Title
Bioconjugation of calcium phosphosilicate nanoparticles for selective targeting of cells in vivo
Method for Ceramide-Elevating Therapeutic Strategies

Teaching Activities

  • Biochemistry of Cancer Taught course 2018
  • Biochemistry of Cancer Taught course 2018
  • Doctoral Thesis Taught course 2018
  • Doctoral Research Taught course 2018
  • Eukaryotic Cell & Devlpmt Biol Taught course 2018
  • Eukaryotic Cell & Devlpmt Biol Taught course 2018
  • Eukaryotic Cell & Devlpmt Biol Taught course 2018
  • Biochemistry of Cancer Taught course 2017
  • Biochemistry of Cancer Taught course 2017
  • Contemp Top Molec/Cell/Biomed Taught course 2017
  • Doctoral Research Taught course 2017
  • Eukaryotic Cell & Devlpmt Biol Taught course 2017
  • Eukaryotic Cell & Devlpmt Biol Taught course 2017
  • Biochemistry of Cancer Taught course 2016
  • Biochemistry of Cancer Taught course 2016
  • Biochemistry of Cancer Taught course 2016
  • Biochemistry of Cancer Taught course 2016
  • Rsrch Exp/MCBS Taught course 2015
  • Education And Training

  • B.S. Biochemistry and Molecular Biology, Colorado State University
  • M.S. Cell and Molecular Biology, Colorado State University
  • Ph.D. Biochemistry and Molecular Biology, University of Alaska
  • Full Name

  • Brian Barth